Nasal spray with antibodies against SARS-CoV-2, which helps to prevent the spread of the virus.

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    Profemina intimate cream
    (available soon)

    Probiotic cream for women health. Lactobacillus crispatus

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    Profemina probiotic capsules
    (available soon)

    Probiotic capsules for women health. Lactobacillus crispatus





Profemina intimate cream
Probiotic cream for women health. Lactobacillus crispatus

Product introduction, purpose

Profemina cream contains beneficial lactic acid bacteria that are found in the vaginal environment of healthy Estonian women. Lactic acid bacteria play an important role in vaginal microbial cohabitation. They help to keep and maintain the balance of these cohabitations, which is necessary for normal functioning of the body and for the prevention of infections.

The bacteria found in Profemina products have undergone thorough research that has lasted for several years at the [i] Health Technology Development Centre, in collaboration with researchers from the University of Tartu. They have a number of useful properties that are necessary to balance the environment of the vagina and to control disorders of vaginal microbial cohabitations, such as bacterial vaginosis and vaginal fungal inflammation.

Profemina intimate cream also contains oil, which has a moisturising and softening effect. Thus, this product is also well suited for problems with vaginal dryness.


Instructions for use

In the evening after washing and before going to bed, apply a fingertip-sized amount of cream to the skin and mucous membranes of your intimate area.

The volume of cream in one package should be used within one month.

Profemina cream can be used as a shorter course of treatment or for a longer period of time.

Profemina cream is also suitable for use together with metronidazole for the treatment of bacterial vaginosis and together with medications for the treatment of fungal inflammation.

List of ingredients

Profemina intimate cream contains four lactic acid bacteria – Lactobacillus crispatus EST-1, Lactobacillus crispatus EST-2, Lactobacillus crispatus EST-3 and Lactobacillus crispatus EST-5.

1 g of Profemina intimate cream contains at least 100 million beneficial lactic acid bacteria.

Warnings and precautions

Keep out of the sight and reach of children.


Preservation conditions

Store in a refrigerator at +4°C.
Use within 4 weeks after opening.


University of Tartu

AS Chemi-Pharm

Competence Centre on Health Technologies


Vaginal Lactobacillus crispatus strains as probiotics for urogenital health

Priority date: 9.10.2018
Priority number: 1816425.


Comparison of detection methods for vaginal lactobacilli. Beneficial Microbes 2015, 6 (5), 747−751.

Characterisation of probiotic properties in human vaginal lactobacilli strains. Microb Ecol Health Dis. 2016 Aug 12, 27: 30484.

Assessment of phenotypic and genotypic antibiotic susceptibility of vaginal Lactobacillus sp. J Appl Microbiol. 2017, 123(2): 524-534.

Potential vaginal probiotics: safety, tolerability and preliminary effectiveness. Beneficial Microbes 2019, 10 (4), 385−393.